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selective estrogen receptor modulators  (Macklin Inc)

 
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    Macklin Inc selective estrogen receptor modulators
    Selective Estrogen Receptor Modulators, supplied by Macklin Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/selective estrogen receptor modulators/product/Macklin Inc
    Average 86 stars, based on 1 article reviews
    selective estrogen receptor modulators - by Bioz Stars, 2026-06
    86/100 stars

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    Selective estrogen receptor modulators reduce invasiveness in PA cell lines AtT‐20 (B) and TtT/GF (C). (A) Representative images of AtT20 (upper panel) and TtT/GF (lower panel) cells stained with DAPI. Note that cell lines were treated with 25% inhibitory concentrations (IC 25 ) of SERMs bazedoxifene, clomiphene, and raloxifene as indicated in Table . Scale bar in (A), for all images, 50 μm. Batimastat, a broad‐range MMP inhibitor, served as positive control. With bazedoxifene in TtT/GF cells, the outlier (o) was excluded from the statistical analysis. Values are given as median, first quartile, and third quartile. Values are obtained from three independent experiments performed in triplicates. t served as statistical test. *Statistically significant difference as compared to control.

    Journal: FEBS Open Bio

    Article Title: Selective estrogen receptor modulators decrease invasiveness in pituitary adenoma cell lines AtT‐20 and TtT/GF by affecting expression of MMP‐14 and ADAM12

    doi: 10.1002/2211-5463.12999

    Figure Lengend Snippet: Selective estrogen receptor modulators reduce invasiveness in PA cell lines AtT‐20 (B) and TtT/GF (C). (A) Representative images of AtT20 (upper panel) and TtT/GF (lower panel) cells stained with DAPI. Note that cell lines were treated with 25% inhibitory concentrations (IC 25 ) of SERMs bazedoxifene, clomiphene, and raloxifene as indicated in Table . Scale bar in (A), for all images, 50 μm. Batimastat, a broad‐range MMP inhibitor, served as positive control. With bazedoxifene in TtT/GF cells, the outlier (o) was excluded from the statistical analysis. Values are given as median, first quartile, and third quartile. Values are obtained from three independent experiments performed in triplicates. t served as statistical test. *Statistically significant difference as compared to control.

    Article Snippet: Selective estrogen receptor modulators (bazedoxifene, clomiphene, and raloxifene) were purchased from Biomol (Hamburg, Germany).

    Techniques: Staining, Positive Control, Control